Academic journal article Iranian Journal of Public Health

The Antibiotic Resistance of Klebsiella Pneumoniae Strains Isolated from Urinary Tract Infections of Shirvan City-North Khorasan in 1392

Academic journal article Iranian Journal of Public Health

The Antibiotic Resistance of Klebsiella Pneumoniae Strains Isolated from Urinary Tract Infections of Shirvan City-North Khorasan in 1392

Article excerpt

Background: Urinary tract infections are the most common infections in humans. Klebsiella pneumoniae is opportunistic pathogen in nosocomial infections. Improvement of Beta- Lactamase (ESBL) in Klebsiella pneumoniae strains lead to the development of antibiotic resistance and mortality in patients. The purpose of this study was to evaluate the antibiotic re- sistance in Klebsiella pneumoniae strains isolated from urinary tract infections in Imam Khomeini Hospital in Shirvan city- North Khorasan in 1392.

Methods: After isolation of K. pneumoniae strains from urine cultures, the antibiotic resistance of the isolates was investi- gated with conventional approaches using the disk diffusion method according to CLSI standards. The standard discs of ampicillin, gentamicin, cefotaxime, cephalexin, cephalothin, nitrofurantoin, ceftriaxone, Nalidixic acid were used.

Results: Through the total of 2584 cases, 255 urine samples (8.9%) were positive, in which 26 (10.1%) Klebsiella pneumoniae was isolated. …

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