Academic journal article Iranian Journal of Public Health

Prevalence of Ctx-M-15 Type Beta-Lactamase Genes in Escherichia Coli Strains Using Pcr Method

Academic journal article Iranian Journal of Public Health

Prevalence of Ctx-M-15 Type Beta-Lactamase Genes in Escherichia Coli Strains Using Pcr Method

Article excerpt

Background: Extended spectrum B-lactamase (ESBL) genes play an important role in spreading B-lactam antibiotic re- sistance in the producing strains expressing these enzymes. The resistance of gram-negative bacteria, such as Escherichia coli, to different antimicrobial agents, has been increasingly reported. This study was conducted to determine the preva- lence of ESBL in Escherichia coli isolates.

Methods: In this cross-sectional study, between March 2013 and February 2014, a total of 120 strains of Escherichia coli were isolated from clinical patient specimens ingeneral Hos- pital. Then, the frequency of ESBL- producing strains was determined by the combined disk method. The presence of the β lactamase gene CTX-M-15 in ESBL was assessed by PCR method.

Results: Atotal of 120 bacteria were isolated from urinary tract infections thatE. coli 98 bacteria were E. …

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