Academic journal article Iranian Journal of Public Health

Antibacterial Activity and Chemical Composition of Medicinal Plant Satureja Bakhtiarica Bung against Multi Drug Resistant Acinetobacter Baumanni (Esbl)

Academic journal article Iranian Journal of Public Health

Antibacterial Activity and Chemical Composition of Medicinal Plant Satureja Bakhtiarica Bung against Multi Drug Resistant Acinetobacter Baumanni (Esbl)

Article excerpt

Background: Historically, plants have provided a source of inspiration for novel drug compounds. Plant derived medi- cines have made large contributions to human health and well being. Of late, there is an increment in the use of herbal products all over the world. Investigation of certain indige- nous plants for their antimicrobial properties may yield useful compounds that may serve as lead molecules or novel chemi- cal entities. Here, the chemical compositions and antibacterial activity of the essential oils obtained from Satureja bakhtiarica bung against multi drug resistant Acinetobater baumanni isolat- ed from burned patients were evaluated.

Methods: Chemical compositions of essential oil were ana- lyzed by gas chromatography mass spectrometry (GC-MS) method. Antibacterial activity of essential oil was evaluated by a well diffusion method. Th e minimum inhibitory concen- tration (MIC) and minimum bactericidal concentration (MBC) were determined by the macrodilution method

Results: The GC-MS spectrums showed 13 compounds, in which the highest chemical composition was related to phe- nol (37. …

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