Academic journal article Iranian Journal of Public Health

Antibacterial Activity of Terminalia Catappa Extract against Escherichia Coli Isolated from Urinary Tract Infections

Academic journal article Iranian Journal of Public Health

Antibacterial Activity of Terminalia Catappa Extract against Escherichia Coli Isolated from Urinary Tract Infections

Article excerpt

Background: Escherichia coli (E.coli) are an important patho- gen in the Urinary Tract Infection (UTI). E. coli is cause of 80% of UTI. Increasing antibiotic usage for E. coli infections has created antibiotic resistance. Subsequently, it is necessary to produce new antibiotics. Medical herbs with anti microbial activity have always been an important role in traditional medicine. The purpose of this study was to determine the antibacterial activity of methanol extract from fruit of Termi- nalia catappa against E. coli isolated from UTI and to compare with effects of selected antibiotics in vitro.

Methods: This research is a descriptive analytic study. First, a sample of methanolic extract from the fruit was prepared by maceration method. Then, its antibacterial activity against 124 isolates of E. coli from 150 samples of UTI was evaluated by well diffusion and then agar serial dilution method. Also, the MIC (Minimum Inhibitory Concentration) of extract was determined. …

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