Academic journal article Iranian Journal of Public Health

Survey of Antibiotic-Resistance Patterns in E.coli Isolated from Patients with Urinary Tract Infection in Rasht

Academic journal article Iranian Journal of Public Health

Survey of Antibiotic-Resistance Patterns in E.coli Isolated from Patients with Urinary Tract Infection in Rasht

Article excerpt

Background: As the E. coli is the most common cause of urinary tract and nosocomial infections, the present study was designed to determine the antimicrobial susceptibility of E. coli in the urine culture of patients admitted to several Hospitals in Rasht.

Methods: In this descriptive case- series study, non- ran- domized purposive sampling was recruited for 195 urine pos- itive sample. Antibiotic resistance profiles (Kirby- Bauer method) were performed according to the CLSI guideline against 19 different antibiotics. The combined disk method was used to detect ESBLs producers E.coli. All the data ana- lyzed in SPSS version 19.

Results: E. coli strains were isolated from 76.93% women and 23.07% men. The majority of strains were isolated from children less than 10 years old. The most antibiotic resistance rates between Penicillins were belonging to Oxacillin, Ampi- cillin and Amoxicillin (100%, 85.64% and 83.58%), respec- tively. Among cephalosporins, Cephalotin and Cefixime were of the highest resistance rate (63.56% and 50.25% respective- ly) and Cefoxitin had the least resistance rate (11.79%). Among quinolones, the most resistance and susceptibility were belonging to Nalidixic- acid (85. …

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