Academic journal article Iranian Journal of Public Health

Frequency of Fluoroquinolone Resistance among Clinical Isolates of Escherichia Coli of Hospitalized Patients in Intensive Care Units of Qazvin, Karaj and Tehran Teaching Hospitals

Academic journal article Iranian Journal of Public Health

Frequency of Fluoroquinolone Resistance among Clinical Isolates of Escherichia Coli of Hospitalized Patients in Intensive Care Units of Qazvin, Karaj and Tehran Teaching Hospitals

Article excerpt

Background: The aim of this study was to generate baseline data on the prevalence of fluoroquinolones resistance amongclinical isolates of Escherichia coli Hospitalized Patients in ICU of Qazvin, Karaj and Tehran teaching hospitals

Methods: In this study, from May 2012 to March 2013,210 E. coli isolates were collected from clinical sample of hospital- ized patients in ICU. All isolates were initially screened for susceptibility to gatiflocxacine, levofloxacine, ofloxa- cine,norfloxacin,ciprofloxacin, nalidixic acid and ESBLs by disk diffusion method according to the CLSI 2013 guideline.

Results: Out of 210 isolates, 127(60.47%) isolates showed the reduction of susceptibility to fluoroquinolone and 111(87.40%) isolate were positive for ESBL production. Based on the study results, the resistance rates were as below: gatifloxacine 111(52. …

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