Academic journal article Iranian Journal of Public Health

Prevalence and Association of Helicobacter Pylori Infection with Gastrointestinal Disease

Academic journal article Iranian Journal of Public Health

Prevalence and Association of Helicobacter Pylori Infection with Gastrointestinal Disease

Article excerpt

Background: Helicobacter pylori is one of the most infections in worldwide, it can colonize the gastric mucosa for years. The effect of Helicobacter pylori to cause gastrointestinal dis- eases is proved and also it can be associated with an increased risk of gastric cancer. This bacterium can have roles in mak- ing different disease such as gastritis, duodenal and peptic ulcer.

Methods: In this study, 230 patients who referred to Hajar hospital of Shahrekord with complain of gastric disorders, diagnosed for undergoing upper endoscopy, demographic data were recorded. 1 biopsy of antrum was collected; biop- sies were checked by 16sRNA and glm genes by polymerase chain reaction for H. pylori, and type of disease was diagnosed by Gastroenterologist.

Results: Of 230 patients, 109 were men (47.4%) and 121 of them were women (52.6%) and the mean age was 44years old. Endoscopic reports showed, 101 patients had gastritis (43.9%), 31patients had peptic ulcer (13.5%) and 14 patients had duodenal ulcer (6.1%), and 81 patients didn't have ulcer disorders (35.2%). The prevalence of hp was 44.3 %(102of 230) in patients. High Frequency of hp positive was in age 31To 50years old (49. …

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