Academic journal article Iranian Journal of Public Health

Antimicrobial Effects of Zinc Oxide and Silver Nitrate Nano Particles on S.aureus, A.baumannii and P.aeroginosa

Academic journal article Iranian Journal of Public Health

Antimicrobial Effects of Zinc Oxide and Silver Nitrate Nano Particles on S.aureus, A.baumannii and P.aeroginosa

Article excerpt

Background: Nano particles have been introduced as novel antimicrobial agents because of their properties that are dif- ferent from their bulk properties. Present study is aimed to investigate antimicrobial activity of silver nitrate and zinc oxide nano particles against three main bacteria responsible for nosocomial infections S.aureus, P.aeroginosa and A.baumanii.

Methods: Solutions of nanoparticles with various concentra- tions were prepared (4000 ppm to 31.25 ppm) in a serial dilu- tion method. Disks with various Concentrations of nanopar- ticles then placed on bacterial cultures for 24 hours, in Diam- eter of inhibition was measured after 24 hours of exposure to nanoparticle in incubator. Diameters of inhibition were com- pared between various concentrations and kinds of bacteria. Analyses of variance were used for comparison of diameter of inhibition between bacteria based on kinds of nanoparti- cles regardless of their concentration.

Results: Nanoparticles of zinc oxide made an inhibitory di- ameter of 13.6 mm in highest concentration to 7 mm in low- est concentration of nanoparticle in S. …

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