Academic journal article Iranian Journal of Public Health

ANTIBIOTIC RESISTANCE OF BACTERIA ISOLATED FROM CLINICAL SPECIMENS IN A UNIVERSITY HOSPITAL IN TEHRAN, Iran

Academic journal article Iranian Journal of Public Health

ANTIBIOTIC RESISTANCE OF BACTERIA ISOLATED FROM CLINICAL SPECIMENS IN A UNIVERSITY HOSPITAL IN TEHRAN, Iran

Article excerpt

Background: Determination of antibiotic resistance of clini- cal isolates can be helpful for delegacy of appropriate drug in urgent experimental remedy of infections.

Methods: We tested antibiotic resistance of 696 non- duplicate clinical isolates were obtained from various clinical samples during eight months (from October 2012 to June 2013) in laboratory of Mostafa Khomaini Hospital (Hospital of Shahed University). We used the disk diffusion method to determine antibiotic resistance.

Results: Totally, the abundance rate of gram negative iso- lates was as much as gram positive isolates and the common sequestrated bacteria were Escherichia-coli (39.7%). The extent of resistance to various antibiotics (Ampicillin, Co-amoxiclav, Cephalothin, Ceftriaxone, Cefotaxime, Piperacillin, Carbeni- cillin, Imipenem, Gentamycin, Tetracycline, Amikacin, Ciprofloxacin, Co-trimoxazole) was different in Escherichia- coli, Klebsiella, Proteuse isolates (8.2% to 96.1%). Despite all isolates of Pseudomonas and Acinetobacter were sensitive to col- istin, all of these isolates were endure to some of the antibiot- ics. About 80.80% of isolated Staphylococcus aureus bacteria were MRSA (Methicillin-resistant Staphylococcus aureus) and resistance of these isolates to Penicillin, Ampicillin, Co- amoxiclav, Cephalothin, Ceftriaxone, Cefotaxime, Gentamy- cin, Tetracycline, Erytromycin, Clindamycin, Ciprofloxacin, Co-trimoxazole was 44. …

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