Academic journal article Iranian Journal of Public Health

Susceptibility of Candida Species Isolated from Oral Candidiasis and Diaper Dermatitis Infections in Neonates to Common Antifungals

Academic journal article Iranian Journal of Public Health

Susceptibility of Candida Species Isolated from Oral Candidiasis and Diaper Dermatitis Infections in Neonates to Common Antifungals

Article excerpt

Background: Oral candidiasia and diaper dermatitis are common infections in children which can be treated with antifungals. However, extensive use of such medications would lead to the creation of resistant candida species. We aimed to evaluate the sensitivity of candida species isolated from oral candidiasis and diaper dermatitis infections in chil- dren.

Methods: In this study, 248 oral candidiasis and diaper der- matitis samples were collected from children referring to private and public clinics in Ilam, Iran. Candida species were identified using standard culture methods. Resistance and sensitivity to amphotericin B, nystatin, ketocona- zole,fluconazole, itraconazole, clotrimazole, and posacona- zole were determined using the CLSI M44-A standard disk diffusion method.

Results: Of the 248 studied samples, 149 were positive for candida, among which the most Candida albicans was the most prevalent (64. …

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