Academic journal article Iranian Journal of Public Health

In-Vitro Antifungal Activity of Echinops Cephalotes on Candida Tropicalis CBS 94 and Using Gc-Ms Method

Academic journal article Iranian Journal of Public Health

In-Vitro Antifungal Activity of Echinops Cephalotes on Candida Tropicalis CBS 94 and Using Gc-Ms Method

Article excerpt

Background: Candida tropicalis is a diploid ascomycetes yeast commonly found on the skin and in digestive tracts healthy human hosts worldwide in recent years

Methods: The objective of the current study was to evaluate the inhibitory effect of Echinops cephalotes against C.tropicalis CBS 94 in laboratory conditions. To this end, in April 2013, Echinops cephalotes were collected from Kom- shecheh, Ardestan. The leaves and stems of these plant were dried in shadow and the acetonic extract were prepared by the Soxhlet apparatus. The antifungal activity were investigat- ed in concentrations of 7.8, 15.8, 31.2, 62.5, 125, and 250 mg/ml through well diffusion method.Minimum Inhibitory Concentration (MIC) and Minimum fingicidal Concentra- tion(MFC) were determined.To identify the components of the plant, the GC-MS technique was used. The results were evaluated by Kruskal Wallis and non-parametric Mann- Whitney statistical tests

Results: The acetonic extract in different concentrations had a remarkable effect on C. …

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