Academic journal article Iranian Journal of Public Health

Molecular Investigation of Genes Encoding Capsular Polysaccharides Type 5 and Type 8 in Staphylococcus Aureus Isolates Collected from Shohada Hospital, Tabriz

Academic journal article Iranian Journal of Public Health

Molecular Investigation of Genes Encoding Capsular Polysaccharides Type 5 and Type 8 in Staphylococcus Aureus Isolates Collected from Shohada Hospital, Tabriz

Article excerpt

Background: Staphylococcus aureus is a major cause of hospital acquired and community-acquired infections. More than 90% of S. aureus strains produce capsular polysaccharides (CPs). Although 11 serotypes of CP have been identified in S. aureus strains, more than 80% of the clinical isolates produce either type 5 CP (CP5) or type 8 CP (CP8).This study was aimed to investigate the CP5 and CP8 genes in S.aureus strains, isolated from surgical wounds of impatients in Shohada hospital - Tabriz from 2010 to 2012.

Methods: The CP5 and CP8 genes was evaluated in 110 clinical specimen of S. aureus strains, isolated from surgical wounds of impatients in Shohada hospital - Tabriz from 2010 to 2012. The CP5 and CP8 genes were detected by PCR method.

Results: The CP5 and CP8 genes were detected in 43 (39/1%) and 64 (52/8%) isolates, respectively, whereas 3 (8/6%) were non-type 5 or non-type 8. …

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