Academic journal article International Journal of Child Health and Human Development

Endocrine Aspects of Children with Disabilities: A Systematic Review

Academic journal article International Journal of Child Health and Human Development

Endocrine Aspects of Children with Disabilities: A Systematic Review

Article excerpt

Context: Children with disabilities are prone to specific endocrine diseases and dilemmas.

Objective: To review systematically the literature about endocrine aspects of childhood disability for the purpose of future research.

Design: Studies published in the last twenty years in PubMed were selected if investigating a list of endocrine conditions in children with disabilities.

Results: Most articles focused on mineral metabolism and bone health and puberty. Regarding bone health disability of several entities was associated with negative effects on bone accretion during childhood and adolescence including vitamin D deficiency and insufficiency, hypercalcemia, hypercalciuria and osteoporosis. Regarding puberty disabilities affected puberty onset, leading to either precocious or delayed puberty. Families often desire and request to interfere with normal girls' menstruation or boys' aggression.

Conclusions: Disability in children show affected endocrine parameters as bone health and timing of puberty. …

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