Academic journal article International Journal of Child Health and Human Development

Trabecular Bone Score and Bone Mineral Density in Ukrainian Normal Women Depending on Duration of Postmenopausal Period

Academic journal article International Journal of Child Health and Human Development

Trabecular Bone Score and Bone Mineral Density in Ukrainian Normal Women Depending on Duration of Postmenopausal Period

Article excerpt

The aim of this study is evaluating trabecular bone score (TBS) and bone mineral density (BMD) in normal women depending on duration of postmenopausal period (PMP).

Materials and methods: We've examined 122 normal women aged 40-79 years (mean age - 56.2±0.8 yrs; mean height - 162.6±0.5 cm; mean weight - 71.5±1.3 kg), who were divided into the groups depending on duration of PMP: without menopause (with normal menstrual cycle) (n=25), 1-3 yrs (n=26), 4-6 yrs (n=12), 7-9 yrs (n=18), 10-12 yrs (n=8), 13-15 yrs (n=4), 16-18 yrs (n=5), more 19 yrs (n=7). BMD of total body, lumbar spine and femoral neck and TBS (TBS iNsight software package, Med- Imaps) were measured by DXA using a densitometer Prodigy, GE.

Results: We have determined the significant decrease of TBS (L1-L4) in women with age (F=4.52; p=0.0001). Duration of PMP has a significant influence on the variability of TBS, BMD of spine and femoral neck (see table 1). The analysis using Scheffe's test shows that TBS was significantly lower in women with duration of PMP more 4 yrs (4-6 yrs (p=0.003), 7-9 yrs (p=0.002), 10-12 yrs (p=0.002), 13-15 yrs (p=0.0003), 16-18 yrs (p=0. …

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