Academic journal article International Journal of Child Health and Human Development

Chronic Liver Disease: Complications and Implications

Academic journal article International Journal of Child Health and Human Development

Chronic Liver Disease: Complications and Implications

Article excerpt

Most liver diseases are life limiting and mandates a multidisciplinary approach. The common result of most chronic liver disease is liver fibrosis, cirrhosis and end-stage liver disease. There are several aims in the management of chronic liver disease. The first is to treat the primary cause of the disease, such as autoimmune hepatitis and viral hepatitis, and to stop the ongoing liver damage. The second aim is to prevent complications of the disease, such as nutritional deficits. The last aim is prediction and management of complications of end-stage disease, namely ascites, esophageal varices and nutritional deficits. At this stage most children are considered for liver transplantation. Children with end-stage liver disease are especially vulnerable to nutritional compromise which can seriously impact long-term outcomes and survival both before and after liver transplantation. …

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