Academic journal article Alcoholism and Psychiatry Research

The Science and Practise of Lithium Treatment

Academic journal article Alcoholism and Psychiatry Research

The Science and Practise of Lithium Treatment

Article excerpt

Title: The Science and Practise of Lithium Treatment Editors: Gin S. Malhi, Marc Masson, Frank Bellivier ISBN: 978-3-319-45921-9 eBook ISBN: 978-3-319-45923-3 DOI: 10.1007/978-3-319-45923-3 Publisher: Springer International Publishing Number of pages: XVI, 342

This book is a comprehensive review of lithium, a simple but powerful molecule with profound benefits to patients. This essential guide is edited and written by eminent international experts Malhi, Masson and Bellivier. All three have decades of experience in the treatment and research of mood disorder. The authors of the chapters are also leading world experts in the field.

Lithium is gold standard for bipolar disorder treatment for decades, since its introduction to clinical practice by John Cade in 1949. and still the best long-term therapy for management of bipolar illness. It is known for the mood stabilizing, anti-suicidal and neuroprotective action. The interest in lithium has grown in recent years (BALANCE study) as it has shown its supremacy over other agents in its main indications. So, this book comes in time reviewing old and adding fresh data.

The book consists of two parts mentioned in the book title. In the first "science" part of the book the authors cover evidencebased knowledge about lithium: properties of lithium ion, pharmacokinetics and pharmacodynamics, lithium therapeutic mechanisms through impact on neurotransmission and gene expression modulation. This part also covers significant drug to drug interactions.

The second part covers „treatment" usage of lithium as a bipolar disorder treatment, and its value in suicide prevention. …

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