Alcohol Research

Journal covering alcohol research.

Articles from Vol. 26, No. 3, Fall

Animal Models for the Genetic Study of Human Alcohol Phenotypes
Animal models can be used to identify novel genes that may contribute to the development of alcoholism in humans and to further extend genetic discoveries made in humans, particularly because researchers can tightly control the genetic and environmental...
Concepts and Terms in Genetic Research-A Primer
It is further remarkable that drunkenness resembles certain hereditary ... diseases. People have long suspected that alcoholism has a genetic component. Research over the last few decades has indicated that 40 to 60 percent of the susceptibility...
Defining Alcohol-Related Phenotypes in Humans: The Collaborative Study on the Genetics of Alcoholism
The Collaborative Study on the Genetics of Alcoholism (COGA) is an innovative, large-scale, multidisciplinary research program launched by the National Institute on Alcohol Abuse and Alcoholism to investigate the genetic components that contribute...
Effects of the Interaction between Genotype and Environment: Research into the Genetic Epidemiology of Alcohol Dependence
Each person's risk of alcohol dependence is determined by the interplay between genetic and environmental risk factors. The interactions between a person's genetic makeup and his or her environment are called "genotype x environment" (GxE) interactions....
Genetic Strategies to Detect Genes Involved in Alcoholism and Alcohol-Related Traits
Developments in genetic technologies are allowing scientists to better study complex disorders such as alcoholism. As described by Drs. Danielle M. Dick and Tatiana Foroud, these strategies include using linkage approaches to identify genes or gene...
Genomic Approaches to the Genetics of Alcoholism
Although researchers have deciphered the entire human genetic material (i.e., the genome), they still must determine which of those sequences actually represent genes, which have regulatory functions, and which cannot yet be assigned a specific...
Is There a Genetic Relationship between Alcoholism and Depression? (Research Update)
It has long been known that alcoholism and depression tend to occur together and that both disorders may run in families. Researchers participating in the Collaborative Study on the Genetics of Alcoholism (COGA) have investigated the prevalence...
Proteomics in Alcohol Research
Researchers are interested not only in the genes that may contribute to the development of alcoholism but also in the functions and activities of the proteins encoded by those genes. The relatively new field of proteomics--the large-scale analysis...
The Collaborative Study on the Genetics of Alcoholism: An Update
Researchers participating in the Collaborative Study on the Genetics of Alcoholism (COGA) are systematically screening all human chromosomes for evidence of DNA regions carrying genes that influence the risk of alcoholism and other related traits....
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