Lupus

lupus (lōō´pəs), noninfectious chronic disease in which antibodies in an individual's immune system attack the body's own substances. In lupus, known medically as lupus erythematosus, antibodies are produced against the individual's own cells, causing tissue inflammation and cell damage. Because the vascular and connective tissue of any body organ may be affected, various symptoms may result. Generalized symptoms include fever, weakness, weight loss, anemia, enlargement of the spleen, and a characteristic butterfly-shaped skin rash on the face. Heart, joint, and kidney disease are common (see nephritis). It is believed that the disease may be triggered by certain drugs or foreign proteins, exposure to ultraviolet radiation, or extreme stress. The disease, which may range from mild to fatal, occurs commonly in young women. It is treated with immunosuppressive drugs and steroids. See immunity; autoimmune disease.

See R. G. Lahita and R. H. Phillips, Lupus: Everything You Need to Know (1998).

The Columbia Encyclopedia, 6th ed. Copyright© 2015, The Columbia University Press.

Lupus: Selected full-text books and articles

The Lupus Book: A Guide for Patients and Their Families By Daniel J. Wallace Oxford University Press, 2005
African-American Women's Health and Social Issues By Catherine Fisher Collins Auburn House, 1996
Librarian’s tip: Chap. 2 "Lupus: The Silent Killer"
A Practice Approach for Identifying Previously Unsuspected Environmental Contributors to Systemic Lupus Erythematosus and Other Complex Diseases. (Commentary) By Foster, Morris W.; Aston, Christopher E Environmental Health Perspectives, Vol. 111, No. 4, April 2003
PEER-REVIEWED PERIODICAL
Peer-reviewed publications on Questia are publications containing articles which were subject to evaluation for accuracy and substance by professional peers of the article's author(s).
Heart Disease in Women By Susan Wilansky; James T. Willerson Churchill Livingstone, 2002
Librarian’s tip: "Systemic Lupus Erythematosus" begins on p. 641
Arthritis: A Take Care of Yourself Health Guide for Understanding Your Arthritis By James F. Fries Perseus Books, 1999 (5th edition)
Librarian’s tip: "Lupus (Systemic Lupus Erythematosus, SLE)" begins on p. 26
Low-Dose Exposure to Inorganic Mercury Accelerates Disease and Mortality in Acquired Murine Lupus By Via, Charles S.; Nguyen, Phuong; Niculescu, Florin; Papadimitriou, John; Hoover, Dennis; Silbergeld, Ellen K Environmental Health Perspectives, Vol. 111, No. 10, August 2003
PEER-REVIEWED PERIODICAL
Peer-reviewed publications on Questia are publications containing articles which were subject to evaluation for accuracy and substance by professional peers of the article's author(s).
The Vocational Implication of Two Common Rheumatic Diseases By Gordon, Phyllis A.; Stoelb, Matthew; Chiriboga, Jennifer The Journal of Rehabilitation, Vol. 63, No. 1, January-March 1997
PEER-REVIEWED PERIODICAL
Peer-reviewed publications on Questia are publications containing articles which were subject to evaluation for accuracy and substance by professional peers of the article's author(s).
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