Magazine article Clinical Psychiatry News

Schizophrenia Three Times as Likely in Celiac Disease Patients

Magazine article Clinical Psychiatry News

Schizophrenia Three Times as Likely in Celiac Disease Patients

Article excerpt

Individuals with celiac disease are more than three times as likely to develop schizophrenia than the general population and more than twice as likely as people with Crohn's disease or ulcerative colitis to do so, Dr. William W. Eaton and his associates reported.

Removal of dietary gluten is neither dangerous nor expensive and effectively treats celiac disease. Dr. Eaton, of Johns Hopkins University, Baltimore, and his associates did not assess whether a gluten-free diet decreased the symptoms of schizophrenia in their study population; however, work by other investigators has shown such an effect (BMJ 328 [7437]:438-39, 2004).

The relationship between schizophrenia and celiac disease was studied in a case sample of 7,997 people who entered a Danish psychiatric facility for the first time between 1981 and 1998 with a diagnosis of schizophrenia. Patients were older than 15 years at the time of their hospitalization, and the identities of their mothers were known.

Each case was matched with 25 controls who did not have schizophrenia, and shared the case patient's year of birth and sex. …

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