Magazine article Clinical Psychiatry News

Focus Is Shifting to Core Negative Symptoms of Schizophrenia

Magazine article Clinical Psychiatry News

Focus Is Shifting to Core Negative Symptoms of Schizophrenia

Article excerpt

SACRAMENTO -- The focus on psychosis in schizophrenia has led to a relative neglect of the other core features, such as negative symptoms and cognitive impairment, but that focus may be changing, Dr. William T. Carpenter said at a meeting on psychotic disorders sponsored by the University of California, Davis.

One major reason for this neglect has been that there are medications used to treat psychosis, but no medications are effective for negative symptoms and cognitive impairment, said Dr. Carpenter, the editor of the Schizophrenia Bulletin, and a professor of psychiatry at the University of Maryland, Baltimore. Much of the research is sponsored by drug companies, and most of the research has been done in psychosis, he said.

The negative symptoms to which Dr. Carpenter said he was referring are sometimes known as the five A's: apathy, alogia, anhedonia, affect restriction, and avolition.

The degree of cognitive impairment and disorganization of thought that a patient has does not appear to be related to the severity of his other symptoms he said.

But cognitive impairment does predict strongly how functional a patient is. And negative symptoms robustly predict quality of life. …

Search by... Author
Show... All Results Primary Sources Peer-reviewed

Oops!

An unknown error has occurred. Please click the button below to reload the page. If the problem persists, please try again in a little while.