Magazine article Nutrition Health Review

Poorer Prognosis for Obese Patients with Breast Cancer

Magazine article Nutrition Health Review

Poorer Prognosis for Obese Patients with Breast Cancer

Article excerpt

Women with breast cancer have more aggressive disease and lower survival rates if they are overweight or obese. Massimo Cristofanilli, M.D., Associate Professor of Medicine in the Department of Breast Medical Oncology at the University of Texas M.D. Anderson Cancer Center in Houston, explained that the more a patient weighs, the more aggressive the disease. Fat tissue may increase inflammation that leads to more aggressive disease.

Dr. Cristofanilli and colleagues observed 606 women with locally advanced breast cancer who were classified by body mass index (BMI) into the following three groups: normal/underweight (24.9 or below), overweight (at least 25 but below 30), or obese (above 30).

At five years, overall survival was 57 percent for the obese women, 56 percent among overweight women, and 67 percent among normal-weight 42 percent for overweight women, and 57 percent for normal weight women.

The rates of inflammatory breast cancer, which previously showed worse outcomes than non-inflammatory breast cancer, among obese women were 45 percent, 30 percent in overweight women, and only 15 percent in normal-weight women. …

Search by... Author
Show... All Results Primary Sources Peer-reviewed

Oops!

An unknown error has occurred. Please click the button below to reload the page. If the problem persists, please try again in a little while.