Magazine article Clinical Psychiatry News

Tea Polyphenols Provide Some Parkinson's Relief

Magazine article Clinical Psychiatry News

Tea Polyphenols Provide Some Parkinson's Relief

Article excerpt

MIAMI BEACH -- Green tea polyphenols taken daily provide minor symptomatic improvement for people with Parkinson's disease, particularly those with more severe disease at baseline, according to findings in a 12-month study. However, the green tea did not provide any disease-modifying effect.

The study lends some confirmation to observations in China of a dose-dependent protective effect of tea drinking against Parkinson's disease, Dr. Piu Chan reported at the congress.

The mechanism that could account for green tea's effects is unknown, but green tea is rich in flavonoids, which make up 30% of its dry weight. In addition, the most abundant compound in green tea, epigallocatechin gallate, protects against toxins in animal models and "may down-regulate expression of pro-apoptotic genes," Dr. Chan said.

To determine the efficacy of green tea polyphenols for slowing progression of Parkinson's disease, he and his colleagues conducted a randomized, double-blind, placebo-controlled, and delayed-start study. They enrolled 410 untreated people with Parkinson's disease at 32 Chinese Parkinson Study Group sites. …

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