Magazine article Journal of Continuing Education Topics & Issues

Arg Bras Endocrinol Metabol.: Eight-Point Glucose Testing versus the Continuous Glucose Monitoring System in Evaluation of Glycemic Control in Type 1 Diabetes

Magazine article Journal of Continuing Education Topics & Issues

Arg Bras Endocrinol Metabol.: Eight-Point Glucose Testing versus the Continuous Glucose Monitoring System in Evaluation of Glycemic Control in Type 1 Diabetes

Article excerpt

CONTEXT: Advantages/disadvantages of continuous vs. discrete glucose monitoring are not well documented. OBJECTIVE: Compare glucose profiles from home meters vs. continuous sensors. DESIGN: Randomized clinical trial conducted by the Diabetes Research in Children Network (DirecNet) to assess the utility of the GlucoWatch G2 Biographer. SETTING: Home glucose measurements. PATIENTS: Two hundred children (age, 7 to < 18 yr) with type 1 diabetes. INTERVENTION: At baseline, subjects were asked to wear the continuous glucose monitoring system (CGMS) sensor and perform meter tests at eight prespecified times of the day (eight-point testing) each for 3 d (2 d using both, 1 d eight-point testing only, 1 d CGMS only). Hemoglobin A1c was measured in a central laboratory. MAIN OUTCOME MEASURE: Six-month hemoglobin A1c. This analysis looked at baseline glucose profiles/hemoglobin A1c. RESULTS: Only 10% of subjects completed full eight-point testing for 3 d, but median CGMS use was 70 h. Mean glucose was lower when measured by the CGMS compared with eight-point testing (183 +/- 37 vs. …

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