Magazine article Clinical Psychiatry News

Only Atypical Major Depressive Disorder Linked to Obesity

Magazine article Clinical Psychiatry News

Only Atypical Major Depressive Disorder Linked to Obesity

Article excerpt

FROM JAMA PSYCHIATRY

The atypical subtype of major depressive disorder is linked to greater risk of obesity, and this link is not found in other subtypes of the illness, a recent study shows.

"For the clinician, the atypical subtype deserves particular attention, because this subtype is a strong predictor of adiposity," Dr. Aurelie M. Lasserre of Lausanne University Hospital in Prilly, Switzerland, and her associates reported online.

"Accordingly, the screening of atypical features and, in particular, increased appetite in individuals with depression is crucial," they wrote (JAMA Psychiatry 2014 June 4 [doi: 10.1001/jamapsychiatry.2014.411]).

After tracking 3,054 participants in Lausanne, Switzerland, for a mean 5.5 years starting in 2003, Dr. Lasserre's team found that those with melancholic, combined, or unspecified major depressive disorder (MDD) showed no greater risk for fat-mass gain or obesity than did those without MDD.

However, individuals with atypical MDD had nearly four times greater odds of obesity (odds ratio, 3.75), with increased body mass index (BMI) and waist circumference in both sexes, and increased fat mass in men, compared with those without MDD.

The researchers found no evidence for medication or physical activity affecting the link between adiposity and atypical MDD.

Of the total sample, 7.6% of the participants met criteria for MDD at baseline, and 36.7% had a previous major depressive episode.

The subtypes among those participants with current MDD included 10% atypical and melancholic combined, 14% atypical, 29% melancholic, and 48% unspecified. …

Search by... Author
Show... All Results Primary Sources Peer-reviewed

Oops!

An unknown error has occurred. Please click the button below to reload the page. If the problem persists, please try again in a little while.