Magazine article Clinical Psychiatry News

MMR Vaccine Does Not Raise Autism Risk

Magazine article Clinical Psychiatry News

MMR Vaccine Does Not Raise Autism Risk

Article excerpt

FROM JAMA

The measles-mumps-rubella vaccine did not raise the risk of developing autism spectrum disorders in a large, diverse, national cohort of children, even among those who had older siblings with autism and thus were at increased risk, according to a report published online April 21 in JAMA.

To examine a possible association between the MMR vaccine and autism, investigators performed a retrospective cohort study using the claims database for a national health plan that treated more than 34 million patients each year. The geographically diverse study population included 95,727 children born in 2001-2007 who had an older sibling and were enrolled for at least 5 years, said Dr. Anjali Jain of the Lewin Group, Falls Church, Va., a health care consulting firm, and her associates.

A total of 1,929 of these study participants (2.01%) had an older sibling with an autism spectrum disorder (ASD). The prevalence of ASD was 1.04% in the entire study sample, which is comparable with the estimated prevalence of 1.5% in the general U.S. population. Among study participants whose older sibling had ASD, the prevalence of the disorder was 6.9%, which is comparable with the estimated prevalence of 6.4%-24. …

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