Magazine article Clinical Psychiatry News

Depression, PTSD Double Dementia Risk for Some Veterans

Magazine article Clinical Psychiatry News

Depression, PTSD Double Dementia Risk for Some Veterans

Article excerpt

AT AAIC 2017

LONDON -- Women veterans with either depression or posttraumatic stress disorder face a doubling in their risk of dementia--and having both increases the risk even more, Kristine Yaffe, MD, reported at the Alzheimer's Association International Conference.

The risk ratios for incident dementia that Dr. Yaffe of the University of California, San Francisco, and her colleagues calculated from their analysis of a cohort of 149,000 older female veterans in the national Veterans Health Administration (VHA) database remained unchanged even when they adjusted for age, education, medical co-morbidities, and other confounders.

"Our work tells us that older women veterans with depression or PTSD should perhaps be monitored more closely or screened for dementia. The question now, really, is would treatment for depression or PTSD somehow delay this? I don't think we have the answer.... Of course, we need to understand the underlying mechanism here, which may someday inform treatment. …

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