Magazine article Clinical Psychiatry News

Depression Is Milder in Patients with Bipolar II. (More Cognitive Abnormalities)

Magazine article Clinical Psychiatry News

Depression Is Milder in Patients with Bipolar II. (More Cognitive Abnormalities)

Article excerpt

BOCA RATON, FLA. -- Depressive episodes in bipolar II disorder appear to differ in key respects from those in bipolar I and major depressive disorder: Cognitive features are more pronounced, and endogenous ones less so, Dr. Patrick Ying said in a poster presentation at a meeting of the New Clinical Drug Evaluation Unit sponsored by the National Institute of Mental Health.

Personality pathology is also more prevalent in bipolar II depression, said Dr. Ying of New York University, New York.

The phenomenologic differences between unipolar and bipolar depression remain uncertain. Dr. Ying and his colleagues evaluated 355 patients experiencing an acute episode of unipolar disorder, 83 in the depressed phase of bipolar I disorder, and 77 in the depressed phase of bipolar II disorder.

Overall, depression in the bipolar II patients was less severe. Mean scores were lower than among bipolar I or unipolar patients on the Beck Depression Inventory, the Hamilton Rating Scale for Depression, and the Clinical Global Impression scale, Dr. Ying said.

Specifically, bipolar II depression appeared to have a less endogenous quality. …

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