Magazine article Medical Economics

Latest Research

Magazine article Medical Economics

Latest Research

Article excerpt

A summary of current clinical articles from that pile on your desk

* Soft Drinks Linked to Pancreatic Cancer in Study

Cancer Epidemiol Biomarkers Prev. 2010;19:447-455. [February 2010]

Consuming two or more soft drinks per week may be associated with a higher risk of pancreatic cancer in middle-aged and elderly Chinese individuals, although results from studies in primarily Caucasian populations have been mixed, according to researchers at Georgetown University Medical Center. Noting that sugary soft drinks can expose the pancreas to high insulin levels that may lead to cancer, researchers assessed the consumption of soft drinks and juice and the risk of pancreatic cancer in 60,524 Chinese men and women in Singapore (mean age, 57.1 years). After up to 14 years of follow-up, the researchers recorded 140 cases of pancreatic cancer. After adjusting for potential confounding factors, individuals who consumed two or more soft drinks per week compared with no soft drinks had a significantly higher risk of pancreatic cancer (hazard ratio, 1.87).

* Diabetes Patients, Doctors May Have Different Hearth Priorities

J of Gen Intern Med. [online] February 2, 2010.

While diabetes patients with comorbidities and their primary care providers are usually in concordance over what their health priorities are, concordance tends to be lower among the least healthy patients and those with non-health competing demands, according researchers at the Department of Veterans Affairs in Ann Arbor, Michigan. They studied 92 primary care providers at nine VA facilities in the Midwest and 1,169 of their patients with diabetes and hypertension. While the patients were asked to rank which of their health conditions was of the greatest concern, providers were asked to rank their patients' comorbidities in terms of likely impact on health outcomes. In all, 714 (72 percent) of the pairs had the patient's most pressing concern ranked within the top three by that patient's physician, with diabetes and hypertension the conditions most frequently cited by both doctors and patients, the researchers found. Pain, depression and breathing problems were more frequently cited by patients than by providers, the investigators note. Concordance was lower when the patients' health status was poor or they had non-health competing demands.

* Steroids in Chronic Obstructive Pulmonary Disease Studied

Chest. 2010;137:318-325. [February 2010]

In patients with chronic obstructive pulmonary disease (COPD), treatment with inhaled corticosteroids (ICS) may have only a modest benefit in preventing disease exacerbations, according to researchers at Postgraduate Institute of Medical Education and Research in Chandigarh, India. They analyzed data on 8,164 patients who were enrolled in 11 studies published between 1998 and 2008.

The researchers' systematic review found that ICS were associated with a modestly reduced risk of exacerbations (relative risk, 0.82), and their sensitivity analysis showed that the benefit was limited to patients with forced expiratory volume in one second values of less than 50 percent (relative risk, 0.79). In addition, metaregression did not show a linear relationship between forced expiratory volume in one second values and a reduction of exacerbations with ICS use.

* Clinicians Need to Be Aware of Patient Herbal Use

JAm Coll Cardiol, 2010;55:515-525. [February 9, 2010]

Health care professionals need to be aware of their patients' use of herbal remedies, which can adversely interact with many common cardiovascular medications, according to researchers at Mayo Clinic. They reviewed the medical literature from 1966 to 2008 for studies on the interactions between cardiovascular medications and herbal remedies recommended by complementary and alternative medicine practitioners or the media for a wide range of conditions, including arthritis, heart failure, depression, and back pain. …

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