Magazine article ASEE Prism

Gut Reaction

Magazine article ASEE Prism

Gut Reaction

Article excerpt

Organoids are small pieces of human organ tissue grown in a lab from stem cells. They're attracting funding and interest because of their potential to make new drug development faster, less expensive, and possibly more accurate than clinical trials on animals and humans - which can cost years and billions to bring a therapy to market. Testing pharmaceuticals first on organoids also could allow researchers to determine if a medicine is potentially toxic early in the process and abandon it. According to Bloomberg Businessweek, 30 percent of drugs that work well on animals end up flunking human trials. Earlier this year, Johns Hopkins University researchers created a small section of human intestine that mimicked a gut suffering from diarrhea, the world's second largest killer of children under 5. …

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