Newspaper article The Journal (Newcastle, England)

Researchers Supporting Child Cancer Centre Bid

Newspaper article The Journal (Newcastle, England)

Researchers Supporting Child Cancer Centre Bid

Article excerpt

Byline: Sarah Scott Reporter

WORLD-LEADING researchers into the cancer that killed teenager Stephen Sutton are supporting a campaign to build a pioneering childhood cancer centre in the North East.

The Newcastle University team leading research into bowel cancer are throwing their support behind the Future Fund, which aims to raise PS5.5m to establish the Newcastle University Centre for Childhood Cancer. Stephen, who won the hearts and minds of the nation with his fundraising for teenage cancer support, had Lynch syndrome - an inherited genetic form of cancer.

The Newcastle team at the Institute of Genetic Medicine played a key role in 1993 in the discovery of the changes in the "mismatch repair genes" which cause this syndrome.

Sir John Burn, Professor of Clinical Genetics at Newcastle University and Consultant Clinical Geneticist for the Newcastle Hospitals, is now gearing up for a new international study that could transform the clinical management of cancer in people with a family history of the disease. His team has established that aspirin significantly reduces the risk of cancer in people with Lynch syndrome.

Their new study, called CaPP3, will establish the optimum dose of aspirin to best treat patients.

Sir John said although Lynch syndrome is extremely rare in young people, there are many areas of overlap in the work of his team and that of the planned Newcastle University Centre for Childhood Cancer.

He said: "I'm really excited about the Future Fund, and our expansion into children's cancer research because there is such close correlation between that work and the research of the genetics team.

"Genetics is key to much of the progress that will be made in the coming years in cancer research, as we can use our expertise to identify the underlying faulty genes that cause many cancers and can use genetic profiling to ascertain the best treatments for patients - young and old. …

Search by... Author
Show... All Results Primary Sources Peer-reviewed


An unknown error has occurred. Please click the button below to reload the page. If the problem persists, please try again in a little while.