Newspaper article The Florida Times Union

Epilepsy Drug Has More Anti-Addiction Uses Company to Seek Human Testing

Newspaper article The Florida Times Union

Epilepsy Drug Has More Anti-Addiction Uses Company to Seek Human Testing

Article excerpt

Scientists at Brookhaven National Laboratory in New York have found that an epilepsy drug that has been shown to block cocaine addiction in animals also works to block their drug-seeking behavior for heroin, alcohol and methamphetamines.

The initial news last year that the drug, vigabatrin, blocked the biochemical effects of cocaine led to hundreds of calls about the substance from addicts.

The drug works by raising levels of GABA, a brain chemical that blocks dopamine. It is thought that dopamine plays an important role in drug abuse by regulating the brain's pleasure and reward centers.

The latest study was published in yesterday's edition of the journal Synapse.

Vigabatrin has yet to be tested in humans. In May, Brookhaven National Laboratory licensed the substance to Davis Pharmaceuticals, a California company developing drugs for Down syndrome, fetal alcohol syndrome, memory loss and now drug addiction. The company is set to file a new drug application with the Food and Drug Administration to test vigabatrin in humans. …

Search by... Author
Show... All Results Primary Sources Peer-reviewed

Oops!

An unknown error has occurred. Please click the button below to reload the page. If the problem persists, please try again in a little while.