A $3.5 million grant will enable researchers at the University of
Oklahoma Health Sciences Center to test a new treatment aimed at
preventing heart disease in American Indians with diabetes.
The Stop Atherosclerosis in Native Diabetics Study, the first
clinical trial in American Indians funded by the National Heart,
Lung and Blood Institute, is a multi-center randomized trial
designed to test a new treatment regimen for high blood pressure and
high cholesterol in American Indian diabetics. The study will
compare a regimen of intensive LDL-cholesterol reduction and
intensive blood pressure lowering with the standard treatment
regimen for hypertension and high cholesterol.
American Indians in the past had very low cardiovascular disease
rates, but it is now the leading cause of death in this population,
with the majority of cardiovascular disease cases in people with
diabetes, according to the Strong Heart Study.
Elisa T. Lee, director of the Center for American Indian Health
Research at the OU Health Sciences Center and principal investigator
of the Stop Atherosclerosis in Native Diabetics Study, participated
in the Strong Heart Study, a 17-year epidemiology study of heart
disease in American Indian communities. In the 13 communities
studied, Lee found the rates of diabetes ranged from 33 percent to
72 percent for people ages 45 to 74. The study found that American
Indian diabetics are two to four times more likely to have
cardiovascular disease than other American Indians.
Bryce Poolaw, clinical director of the Lawton Indian Hospital,
will serve as co-principal investigator for the study. The Center
for American Indian Health Research will serve as the data-
coordinating center for the study, which includes sites in Phoenix
and Chinle, Ariz., and Rapid City and Pine Ridge, S.D.
Foundation for Digestive Research
Philip Miner, president and medical director of the Oklahoma
Foundation for Digestive Research, has put together a gallery of
photographs, which are not related to his professional work, taken
while touring the world. The collection will be on display during
the foundation's annual open house today.
Oklahoma Heart Hospital
Oklahoma Heart Hospital is the first in the state to take part in
a new national clinical trial, ICE-IT, Intravascular Cooling
Adjunctive to Primary Coronary Intervention. By inserting a cold-
tipped catheter into blood vessels, physicians may be able to cool
the body by several degrees following a heart attack, preserving
heart tissue and decreasing any damage to the heart.
Studies have shown that hypothermia can reduce brain damage after
the onset of a stroke. Now, officials want to see if the same thing
holds true for heart attack victims.
A catheter with a flexible metallic element at the tip allows
physicians the ability to rapidly cool the blood and later restore a
patient to normal body temperature in an efficient and predictable
manner. Innercool Therapies, the San Diego-based company behind the
clinical trials, got the study under way this fall.
For more information about the study, call Oklahoma Foundation
for Cardiovascular Research at 608-1280.
Cystic Fibrosis Foundation
Mark and Diane Harvey of Edmond have been appointed the Oklahoma
chairpersons for the Cystic Fibrosis Foundation's volunteer
leadership initiative: 2,003 for 2003. The goal of this campaign is
to recruit 2,003 new volunteers nationwide to the fight against
cystic fibrosis. The Harveys will be in charge of leading this
effort in the Oklahoma community and growing the foundation's base
of support in the state.
Because the Cystic Fibrosis Foundation relies exclusively on
individual and corporate donations, growing its base of volunteers
is key to raising the funds necessary to develop new treatments and
improving the quality of life for people with cystic fibrosis. …