Medical Research Grants Update; in the Lab; Area Scientists Tackle a Variety of Projects

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Following is a list of some of the medical research grants awarded to scientists in the area.

University of Missouri St. Louis, Innovative Technology Enterprises

The scientist Matthew MacEwan, chief scientific officer of OsteoVantage.

The grant $150,000 from the National Science Foundation.

The study Development of a screw capable of improving bone formation and bone growth in the spine during spinal fusion procedure.

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Southern Illinois University School of Medicine, Carbondale and Springfield

The scientist Dr. Michael Pranzatelli, professor of neurology and director of the National Pediatric Myoclonus Center.

The grant $205,081 from Questcor Pharmaceuticals Inc.

The study Determine the role of specific chemicals in the blood and spinal fluid on brain inflammation from pediatric opsoclonus- myoclonus syndrome. Its a rare disease triggered by a body-cavity tumor called a neuroblastoma, that renders a previously normal child unable to talk, sit, walk or sleep, causing uncontrollable shaking and eye movements.

The scientist Farid Kadyrov, assistant professor of biochemistry and molecular biology.

The grant $232,800 from National Institute of General Medical Studies.

The study Investigate the impact of the interplay of DNA mismatch repair and the nucleosomal environment on genetic stability and efficiency of two common anti-cancer drugs.

The scientist Jolio Copello, associate professor of pharmacology.

The grant $142,469 from the American Heart Association.

The study Get a clearer understanding of the cause of faulty calcium regulation inside the heart cells that is associated with arrhythmia, heart failure and other cardiac conditions.

The scientist Donald Torry, professor and chair of medical microbiology, immunology and cell biology.

The grant $436,500 from the National Institute of Child Health and Human Development.

The study Determine why placental growth factor is not being produced properly and causes restriction of maternal blood vessels in women with preeclampsia and intrauterine growth retardation. Also, how inflammatory processes, which are common during preeclampsia, contribute to malfunction of the placenta.

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Washington University School of Medicine

The scientist Gautam Dantas, assistant professor of pathology and immunology, and biomedical engineering.

The grant $2.1 million from the National Institute of Diabetes and Digestive and Kidney Diseases.

The study Metagenomic engineering of probiotic bacteria to improve intestinal colonization dynamics and relative fitness.

The scientist Gautam Dantas, assistant professor of pathology and immunology, and biomedical engineering.

The grant $100,000 from the Kenneth Rainin Foundation.

The study Synthetic engineering of enhanced fitness and adhesion properties in probiotics for the treatment of inflammatory bowel disease. …