Newspaper article International Herald Tribune

Radical Shift for U.S. Patients on Cholesterol Drugs ; Those Told to Take Statins to Lower a High Count Will No Longer Be Given Targets

Newspaper article International Herald Tribune

Radical Shift for U.S. Patients on Cholesterol Drugs ; Those Told to Take Statins to Lower a High Count Will No Longer Be Given Targets

Article excerpt

Patients on statins will no longer need to lower their cholesterol levels to numerical targets. Simply taking the right dose will be sufficient, experts say.

The United States' leading heart organizations have released new guidelines that will fundamentally reshape the use of cholesterol- lowering statin medicines, which are now prescribed for a quarter of Americans over 40. Patients on statins will no longer need to lower their cholesterol levels to specific numerical targets monitored by regular blood tests, as has been recommended for decades. Simply taking the right dose of a statin will be sufficient, the guidelines say.

The new approach announced Tuesday divides people needing treatment into two broad risk categories. Those at high risk because, for example, they have diabetes or have had a heart attack should take a statin except in rare cases. People with extremely high levels of the harmful cholesterol known as LDL -- 190 or higher -- should also be prescribed statins. In the past, people in these categories would also have been told to get their LDL down to 70, something no longer required.

Everyone else should be considered for a statin if his or her risk of a heart attack or stroke in the next 10 years is at least 7.5 percent. Doctors are advised to use a new risk calculator that factors in blood pressure, age and total cholesterol levels, among other things.

"Now one in four Americans over 40 will be saying, 'Should I be taking this anymore?"' said Dr. Harlan M. Krumholz, a cardiologist and professor of medicine at Yale who was not on the guidelines committee.

The new guidelines, formulated by the American Heart Association and the American College of Cardiology and based on a four-year review of the evidence, simplify the current complex, five-step process for evaluating who needs to take statins. In a significant departure, the new method also counts strokes as well as heart attacks in its risk calculations, a step that will probably make some additional people candidates for the drugs.

It is not clear whether more or fewer people will end up taking the drugs under the new guidelines, experts said. …

Search by... Author
Show... All Results Primary Sources Peer-reviewed

Oops!

An unknown error has occurred. Please click the button below to reload the page. If the problem persists, please try again in a little while.