Newspaper article Manchester Evening News

New Treatments for Cancer Now Are a Step Closer

Newspaper article Manchester Evening News

New Treatments for Cancer Now Are a Step Closer

Article excerpt

PERSONALISED treatments for leukaemia have come a step closer after a British study on the role gene mutations play in blood cancers.

Scientists from the University of Birmingham analysed abnormal white blood cells taken from patients with acute myeloid leukaemia (AML), an aggressive form of the disease affecting about 2,600 people each year in the UK.

The team identified critical genetic "trigger points" that influenced the cells' identity and behaviour. The research focused on myeloid cells, key components of the immune system that fight off bacterial infections and parasites.

Co-author Prof Peter Cockerill said: "Doctors in Birmingham are already testing AML patients for the many different mutations that cause AML. However, now they know which genes are the most important for each type of AML. …

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