Health and Mortality among Elderly Populations

By Graziella Caselli; Alan D. Lopez | Go to book overview

tion between serum cholesterol and stroke.18 They also argue that even if the causal mechanisms were satisfactorily established, the potentially negative effects of increased serum cholesterol levels on other cardiovascular diseases could readily outweigh the presumed positive effect on stroke. Whether this scepticism is warranted in the case of Japan remains to be seen.


Acknowledgements

The authors gratefully acknowledge partial support from the Japan Foundation. We would like to thank Shigemi Kono, Anne Pebley, Lorenzo Moreno, and Rachel Weinstein for their comments and advice and Maryann Belanger for her invaluable assistance in locating and providing reference materials.


REFERENCES

Akiba S. and Hirayama T. ( 1990), "'Cigarette Smoking and Cancer Mortality Risk in Japanese Men and Women: Results from Reanalysis of the Six-Prefecture Cohort Study Data'", Environmental Health Perspectives, 87: 19-26.

Benfante R. ( 1992), "'Studies of Cardiovascular Disease and Cause-Specific Mortality Trends in Japanese-American Men Living in Hawaii and Risk Factor Comparisons with other Japanese Populations in the Pacific Region: A Review'", Human Biology, 64:791-805.

Blackburn H. and Jacobs D. R., Jr. ( 1989), "'The Ongoing Natural Experiment of Cardiovascular Diseases in Japan'", Circulation, 79: 718-20.

Fries J. F. ( 1980), "'Aging, Natural Death, and the Compression of Morbidity'", New England Journal of Medicine, 303: 130-5.

Fukawa T. ( 1993), 'Implications of Population Ageing and Health Trends among the Elderly for Japanese Society and Economic Growth', paper presented to the United Nations, World Health Organization, and IUSSP Committee on Adult Mortality Conference, 'Health and Mortality Trends Among Elderly Populations: Determinants and Implications', June 1993, Sendai City, Japan.

Gordon T. ( 1957), "'Mortality Experience among the Japanese in the United States, Hawaii, and Japan'", Public Health Reports 72: 543-53.

Goto Y. ( 1992), "'Changing Trends in Dietary Habits and Cardiovascular Disease in Japan: An Overview'", Nutrition Reviews, 50: 398-401.

Hara H., Egusa G., Yamane K., and Yamakido M. ( 1992), "'Diabetes and Diabetic Macroangiopathy in Japanese-Americans'", in D. F. Roberts, N. Fujiki, and K. Torizuka (eds.), Isolation, Migration and Health ( London: Cambridge University Press), ch. 20.

Hasuo Y., Ueda K., Kiyohara Y., Wada J., Kawano H., Kato I., Yanai T., Fujii I., Omae T., and Fujishima M. ( 1989), "'Accuracy of Diagnosis on Death Certificatesfor Underlying Causes of Death in a Long-Term Autopsy-Based Population Study in Hisayama, Japan; with Special Reference to Cardiovascular Diseases'"

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18
The hypothesis relating serum cholesterol to stroke is that a minimum level of serum cholesterol is needed to maintain the health of the arterial walls. Very low levels are thought to result in damage of the cell membranes in the walls and thereby an increased risk of cerebral haemorrhage ( Blackburn and Jacobs, 1989).

-178-

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