The genetics of type 2 diabetes, MODY, and other syndromesWilliam E Winter
The forms of non-insulin-dependent-non-autoimmune diabetes affecting children include:
|2. maturity-onset diabetes of the young (MODY)|
|3. mitochondrial diabetes and|
|4. other specific types of diabetes such as diabetes secondary to cystic fibrosis.|
The genetics of each condition is discussed below.
Type 2 diabetes: genetic overview
There is convincing evidence that genetics plays a major role in the etiology of type 2 diabetes in adults.
1 Among people with type 2 diabetes, there is often a very strong family history of similarly affected individuals: familial aggregations of type 2 diabetes are common. Because lifestyle patterns that lead to obesity are so ingrained into everyday life and family habits, it is often difficult to separate nature versus nurture.