The physician who cannot inform his patient what would be the probable issue of his complaint if allowed to follow its natural course, is not qualified to prescribe any rational treatment for its cure.
Hippocrates (460-373 BC) 1
Prognoses are the disliked stepchildren of medicine.…The more the prognoses refer to the future, the more they resemble prophecies.…Individual prognoses are necessary in every medical decision, and, beyond that, they even legitimize every medical act. If there is no prognostic relevance, no intervention can be justified.The methodology of prognosis forms the core of medical practice and a humane medicine.
Claudia Wieseman (1998) 2