Anxiety Disorders Comorbid with Depression: Social Anxiety Disorder, Post-Traumatiac Stress Disorder, Generalized Anxiety Disorder, and Obsessive-Compulsive Disorder

By Dan J. Stein; Eric Hollander | Go to book overview

Treatment

Psychopharmacology dogma has long indicated that the antidepressants are effective in depression, whereas the benzodiazepines are useful in anxiety. A number of developments have, however, resulted in such dogma being thoroughly overturned. First, the significant problems associated with benzodiazepines have been increasingly appreciated. Second, it has become more and more apparent that certain antidepressants are effective for both the mood and anxiety disorders. In this chapter we review this literature in more detail.


Benzodiazepines

The advantage of the benzodiazepines is that they are quick-acting medications, which rapidly decrease anxiety symptoms. Furthermore, these agents, particularly the high-potency benzodiazepines, have been found to be effective in the treatment of panic disorder and perhaps social anxiety disorder. There is also a small literature on their use in obsessive-compulsive disorder (OCD).

Problems with the benzodiazepines include sedation and dependence, e.g. there is persuasive evidence that patients on benzodiazepines are more likely to be involved in motor vehicle accidents. In addition, the difficulties in discontinuing medication in patients who have

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Anxiety Disorders Comorbid with Depression: Social Anxiety Disorder, Post-Traumatiac Stress Disorder, Generalized Anxiety Disorder, and Obsessive-Compulsive Disorder
Table of contents

Table of contents

  • Acknowledgements ii
  • Title Page iii
  • Contents v
  • Preface vii
  • Comorbidity 1
  • Symptoms/Epidemiology 12
  • Psychobiology 29
  • Treatment 43
  • References 56
  • Index 69
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