Autism, Brain, and Environment

By Richard Lathe | Go to book overview
Contents
PREFACE13
ACKNOWLEDGEMENTS14
Chapter1Introduction15
Chapter 2Autism and Autism Spectrum Disorders: An Introduction to the Problem of Recognition and Diagnosis20
Pervasive developmental disorders21
Early diagnosis33
Autism, a preferred diagnosis?34
The broader phenotype35
Is there really such a thing as autism? Subtypes35
Chapter 3Genetic Contribution to Autistic Spectrum Disorders: Diversity and Insufficiency37
Genetic predisposition to ASD37
How important are genes in ASD? Heritability38
Insufficiency of genetic predisposition40
The search for new genes40
Potential ASD genes42
Problems with the genome approach44
The patchwork genome45
Epigenetics and brain disorders45
Genes and environment46
Chapter 4New Phase Autism: Rising Prevalence48
The debate48
Increasing prevalence50
Why do different studies seem to give different rates?51
Potential confounding factors52
Other evidence addressing a rise53
Summary of observations58
Is there an epidemic of autism?58
Conclusion. The rise may be real: new phase autism59
Chapter 5Brain Abnormalities: Focus on the Limbic System61
Brain structure63
Studying brain structure: techniques64

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