In August 1964 Bernier met with the director of the National Library of Medicine, the associate director of the library, and an epidemiologist from Columbia University. During the meeting, the epidemiologist said that he had just read the most important paper on heart disease "to come down the pike" in ten years. He described the work of Yudkin and Roddy ( 1964) on the intakes of sucrose by male patients with atheromatous vascular disease or with a first-known attack of myocardial infarction (coronary heart disease) as contrasted with the diets of an age-matched control group of male patients with conditions such as fracture of a limb or torn meniscus of the knee joint, and with other control subjects who were apparently healthy men living in the western area of London. The epidemiologist said that he had data confirming that of Yudkin. In November 1964 the senior author read the paper (published in the The Lancet 11, 4 July 1964, 6-8). In this paper the patients with peripheral arterial disease or surviving a recent myocardial infarction were eating nearly twice as much sucrose as was the control group. The probability that this result could have occurred by chance was calculated to be less than one in two thousand. Also, in the control group of patients (and healthy men), with increasing age there was a decreasing proportion of the subjects who had a high intake of sucrose. This could have been due to the fact that the older control subjects had died of a coronary.