Who Can Cure the Pharmaceuticals? Margaret Cook on How the Influence of Drugs Companies Has Seeped, through Their Control of Research and Even of the Official Regulator, into the Fabric of Medical Life

By Cook, Margaret | New Statesman (1996), November 15, 2004 | Go to article overview

Who Can Cure the Pharmaceuticals? Margaret Cook on How the Influence of Drugs Companies Has Seeped, through Their Control of Research and Even of the Official Regulator, into the Fabric of Medical Life


Cook, Margaret, New Statesman (1996)


"Trying to force a financial camel through the eye of a scientific needle" was the metaphor used to describe the Herculean task of regulating pharmaceutical companies. This was the view of one witness to last month's session of the House of Commons health select committee on the influence of the pharmaceutical industry. The session was an eye-opener, shedding light on doctors who prescribe medication without having all the necessary information for that purpose; and on a weak and uncoordinated regulatory system that enables the pharmaceutical industry to further its interests without sufficient regard to public health.

The industry's influence has seeped into the fabric of medical life. It has tapped the worst of human motives-money, power and glory. A megabillion-dollar global business, it has a Big Brother potency outstripping that of governments, at which it has been known to snap its fingers as it breaks safety rules to suit its own commercial ends.

While some pharmaceutical bosses admit freely that their prime motive is profit, the success of the industry derives from the fostered perception that it exists primarily as a public good. Many drug reps I have met positively glowed with missionary zeal as they pursued their personal targets. Medications are seen as an unqualified good by the naive: one question posed to witnesses to the committee was: "Does not every new drug on the market constitute a new cure?" This is a dangerous misconception, and one that needs to be demolished. The consistent playing down of serious, even fatal, side effects of drugs has been achieved in part with the collusion of the medical profession; but the industry's share of the blame is much greater. Not only were pharmaceutical companies dragging their heels when it came to reporting side effects to regulators--side effects including rates of suicide among children treated with certain antidepressants--one doctor witness had been offered a bribe worth two years' salary not to publish research that detracted from a company's drugs marketing profile. Other captive doctor lecturers have found, on glamorous, lucrative promotional trips, that the payments dry up smartly if they dare go off-company message. Such bribery has become commonplace.

After the thalidomide disaster in the Sixties, the medical authorities established a yellow-card system of voluntary reporting by doctors to the Committee on Safety of Medicines (CSM). It was assumed that, in a caring profession, the system would work (as it might well have done if it had been linked with merit awards). But altruism proved a weak motivator. As was discovered after a Panorama documentary on Seroxat, if you take information direct from sufferers you get an avalanche of details. It seems that the CSM (now reincarnated as the Medicines and Healthcare products Regulatory Agency, or MHRA) is composed mainly of "experts", who have an interest, personal or otherwise, in the major pharmaceutical companies. Consumers are nowhere to be seen. The MHRA has become so fused to the industry it is supposed to regulate that it has lost its own identity, meekly adopting the rules of commercial secrecy and inhibited by the terrible penalties, including imprisonment, of disclosing sensitive information. Industry is adept at using the threat of litigation to suppress even the thought of whistle-blowing.

The effect of the incestuous relationship between the industry and the government regulator is that negative and harmful side effects are not disclosed to professionals or the public, even when they are life-threatening; such as the higher rate of suicide linked to some psychoactive drugs, and strokes or heart attacks associated with the anti-inflammatory Vioxx, recently withdrawn.

Distinguished specialists and professors at prestigious institutes, in pharma-speak called "opinion leaders", are groomed for engagement. …

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Who Can Cure the Pharmaceuticals? Margaret Cook on How the Influence of Drugs Companies Has Seeped, through Their Control of Research and Even of the Official Regulator, into the Fabric of Medical Life
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