Cathryn Edmonds: The Effect of Infliximab Treatment on Motor and Process Skill Performance in Patients with Rheumatoid Arthritis
Edmonds, Cathryn, British Journal of Occupational Therapy
The effect of Infliximab treatment on motor and process skill performance in patients with rheumatoid arthritis.
University of Plymouth, 2007. MSc in Occupational Therapy.
Rheumatoid arthritis is a chronic and destructive autoimmune disease characterised by inflammation of the synovial tissue of the joints. Its course is variable and unpredictable and, over time, leads to structural damage to joints and soft tissue, as well as functional impairment.
Maintenance of functional ability is a major aim of treatment in rheumatoid arthritis. The high cost of rheumatoid arthritis to both patient and society demands that a drug must be subjected to a reliable functional outcome measure (Guillemin 2000). To demonstrate that a drug is able to control a disease, it must show that it can contribute to the maintenance of or improvement in function.
A pilot study was carried out to determine whether participants with rheumatoid arthritis, who were treated with anti-tumour necrosis factor alpha therapy (anti-TNF[alpha]), namely Infliximab, demonstrated a change in functional performance at 1 month and 3 months after Infliximab treatment commenced. …