Neuroimaging Studies: Disease Response or Cause? (Chicken-or-Egg Question about Results)

By Boschert, Sherry | Clinical Psychiatry News, December 2001 | Go to article overview

Neuroimaging Studies: Disease Response or Cause? (Chicken-or-Egg Question about Results)


Boschert, Sherry, Clinical Psychiatry News


HONOLULU -- Most neuroimaging studies that compare normal brains with those of people with neuropsychiatric disorders conclude that the differences seen identify the causes of the psychopathology.

If subsequent studies show that medication relieves symptoms and makes brains with psychopathology look normal again, most researchers conclude mat the drug has treated the cause of the disorder.

It's not that simple, Elizabeth E. Gerard said in a poster presentation at the annual meeting of the American Academy of Child and Adolescent Psychiatry. What you see may not be the only cause of the disorder, or may not be the cause at all. It could be a response to the disorder. In that case, you would expect medication to correct the differences seen between brains, since eliminating the symptoms also would eliminate the response, said Ms. Gerard, a Doris Duke Fellow in child psychiatry at Columbia University, New York.

If it is true that some neuroimaging studies demonstrate neurologic responses to a syndrome, their findings could help identify ways that people recover or might recover from the illness, she said.

Ms. Gerard and her mentor, Dr. Bradley S. Peterson, based their conclusions on a review of the literature, which included findings from two studies of patients with Tourette's syndrome led by Dr. Peterson. They chose Tourette's syndrome as a useful model to illustrate their point because 90% of children with the disorder either recover completely or have only mild symptoms as adults. "Something is going on in those patients that helps them recover, and we presume that there's a neural basis for" the remision of their symptoms, she said.

In the first functional MRI study of Tourettes syndrome, images taken of 22 subjects with the disorder while they were attempting to suppress tics were compared with those of the same subjects while they were allowed to express their tics (Arch. …

The rest of this article is only available to active members of Questia

Already a member? Log in now.

Notes for this article

Add a new note
If you are trying to select text to create highlights or citations, remember that you must now click or tap on the first word, and then click or tap on the last word.
One moment ...
Default project is now your active project.
Project items
Notes
Cite this article

Cited article

Style
Citations are available only to our active members.
Buy instant access to cite pages or passages in MLA 8, MLA 7, APA and Chicago citation styles.

(Einhorn, 1992, p. 25)

(Einhorn 25)

(Einhorn 25)

1. Lois J. Einhorn, Abraham Lincoln, the Orator: Penetrating the Lincoln Legend (Westport, CT: Greenwood Press, 1992), 25, http://www.questia.com/read/27419298.

Note: primary sources have slightly different requirements for citation. Please see these guidelines for more information.

Cited article

Neuroimaging Studies: Disease Response or Cause? (Chicken-or-Egg Question about Results)
Settings

Settings

Typeface
Text size Smaller Larger Reset View mode
Search within

Search within this article

Look up

Look up a word

  • Dictionary
  • Thesaurus
Please submit a word or phrase above.
Print this page

Print this page

Why can't I print more than one page at a time?

Help
Full screen
Items saved from this article
  • Highlights & Notes
  • Citations
Some of your highlights are legacy items.

Highlights saved before July 30, 2012 will not be displayed on their respective source pages.

You can easily re-create the highlights by opening the book page or article, selecting the text, and clicking “Highlight.”

matching results for page

    Questia reader help

    How to highlight and cite specific passages

    1. Click or tap the first word you want to select.
    2. Click or tap the last word you want to select, and you’ll see everything in between get selected.
    3. You’ll then get a menu of options like creating a highlight or a citation from that passage of text.

    OK, got it!

    Cited passage

    Style
    Citations are available only to our active members.
    Buy instant access to cite pages or passages in MLA 8, MLA 7, APA and Chicago citation styles.

    "Portraying himself as an honest, ordinary person helped Lincoln identify with his audiences." (Einhorn, 1992, p. 25).

    "Portraying himself as an honest, ordinary person helped Lincoln identify with his audiences." (Einhorn 25)

    "Portraying himself as an honest, ordinary person helped Lincoln identify with his audiences." (Einhorn 25)

    "Portraying himself as an honest, ordinary person helped Lincoln identify with his audiences."1

    1. Lois J. Einhorn, Abraham Lincoln, the Orator: Penetrating the Lincoln Legend (Westport, CT: Greenwood Press, 1992), 25, http://www.questia.com/read/27419298.

    Cited passage

    Thanks for trying Questia!

    Please continue trying out our research tools, but please note, full functionality is available only to our active members.

    Your work will be lost once you leave this Web page.

    Buy instant access to save your work.

    Already a member? Log in now.

    Search by... Author
    Show... All Results Primary Sources Peer-reviewed

    Oops!

    An unknown error has occurred. Please click the button below to reload the page. If the problem persists, please try again in a little while.