Smoking Causes Bladder Changes

Nutrition Health Review, Spring 1990 | Go to article overview

Smoking Causes Bladder Changes


Smoking Causes Bladder Changes

Changes in the number of cells and in the presence of cells with atypical nuclei in the epithelium of the urinary bladder appear to be associated with cigarette smoking, according to the authors of this study from the Veterans Administration Medical Center in East Orange, N.J., and the American Cancer Society.

Histologic examinations were performed in random order on 6,503 slides of urinary bladder epithelium obtained at autopsy from 282 subjects (70% men, 30% women) ranging in age from 10 to 94 years. History of smoking and of artificial sweetener use was obtained from family members of each subject.

Slides showing cells with 50% or more atypical nuclei were found in 4.3% of those who had never smoked regularly, in 67.2% who had smoked fewer than 20 cigarettes a day, in 72.2% who smoked 20 to 39 cigarettes a day, and in 88.4% who smoked 40 or more cigarettes a day. …

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