Prozac Approved for Major Depressive Disorder, OCD in Children and Teens. (Patients Aged 7-17 Years)

By McNamara, Damian | Clinical Psychiatry News, February 2003 | Go to article overview

Prozac Approved for Major Depressive Disorder, OCD in Children and Teens. (Patients Aged 7-17 Years)


McNamara, Damian, Clinical Psychiatry News


The Food and Drug Administration approved Prozac for treating major depressive disorder and obsessive-compulsive disorder in children and adolescents aged 7-17 years.

"It is reassuring for physicians that a certain threshold of evidence has been reached in terms of safety and efficacy" said Dr. Christopher Jon Kratochvil of the department of psychiatry at the University of Nebraska Medical Center, Omaha. "The most important thing is that a good clinical evaluation be conducted before use of any psychotropic in children."

The new indication may help primary care physicians decide which antidepressant to use in young patients, Dr. Kratochvil said. "It will be reassuring for physicians in the primary care world because they may have less experience with psychotropic medications in general."

Prozac (fluoxetine) is the first selective serotonin reuptake inhibitor (SSRI) to be approved for treating depression in this population, and the third SSRI indicated for pediatric obsessive-compulsive disorder (OCD). Sertraline and fluvoxamine already are indicated.

The new pediatric indications are based on two placebo-controlled clinical trials. …

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