Research: Some Infants Prone to Early Birth

By Avant, Lydia Seabol | The Tuscaloosa News, February 7, 2015 | Go to article overview

Research: Some Infants Prone to Early Birth


Avant, Lydia Seabol, The Tuscaloosa News


Some babies may be predisposed to being born prematurely -- meaning their DNA causes them to be born too soon, according to new research from the University of Alabama at Birmingham.

Dr. Joseph Biggio, professor and director of the UAB division of maternal-fetal medicine in the Department of Obstetrics, recently analyzed the number of copies of certain segments of DNA in the blood or saliva of hundreds of babies and their mothers. His research found that a baby was anywhere from two to 11 times more likely to be born before 34 weeks of gestation if a certain four genes were duplicated or if any seven genes were deleted.

"These findings may help explain what triggers early labor in some women even when they've done everything right during pregnancy and there's no obvious cause for an early birth," said Dr. Edward R.B. McCabe, March of Dimes chief medical officer, in a statement. "The hope is that this finding may one day lead to a screening test to help identify which babies are at a higher risk of an early birth."

Biggio was recognized last week in San Diego by the March of Dimes, receiving the Best Research in Prematurity award.

The genes may not directly cause a preterm birth, but they could make the baby more susceptible to an infection or other environmental factors that trigger early labor, Biggio said.

"We don't know exactly that it's the genes in these areas," Biggio said. "It may be something else, but these changes are in the areas of these genes, and that's certainly the first place to start looking."

It may also help explain why treatment with progesterone, a naturally occurring hormone in pregnancy shown to prevent some preterm births, works for only about one-third of women.

"We think we are treating the mother with progesterone, but perhaps we are actually treating the baby or changing the fetal- immune response," Biggio said. …

The rest of this article is only available to active members of Questia

Already a member? Log in now.

Notes for this article

Add a new note
If you are trying to select text to create highlights or citations, remember that you must now click or tap on the first word, and then click or tap on the last word.
One moment ...
Default project is now your active project.
Project items
Notes
Cite this article

Cited article

Style
Citations are available only to our active members.
Buy instant access to cite pages or passages in MLA 8, MLA 7, APA and Chicago citation styles.

(Einhorn, 1992, p. 25)

(Einhorn 25)

(Einhorn 25)

1. Lois J. Einhorn, Abraham Lincoln, the Orator: Penetrating the Lincoln Legend (Westport, CT: Greenwood Press, 1992), 25, http://www.questia.com/read/27419298.

Note: primary sources have slightly different requirements for citation. Please see these guidelines for more information.

Cited article

Research: Some Infants Prone to Early Birth
Settings

Settings

Typeface
Text size Smaller Larger Reset View mode
Search within

Search within this article

Look up

Look up a word

  • Dictionary
  • Thesaurus
Please submit a word or phrase above.
Print this page

Print this page

Why can't I print more than one page at a time?

Help
Full screen
Items saved from this article
  • Highlights & Notes
  • Citations
Some of your highlights are legacy items.

Highlights saved before July 30, 2012 will not be displayed on their respective source pages.

You can easily re-create the highlights by opening the book page or article, selecting the text, and clicking “Highlight.”

matching results for page

    Questia reader help

    How to highlight and cite specific passages

    1. Click or tap the first word you want to select.
    2. Click or tap the last word you want to select, and you’ll see everything in between get selected.
    3. You’ll then get a menu of options like creating a highlight or a citation from that passage of text.

    OK, got it!

    Cited passage

    Style
    Citations are available only to our active members.
    Buy instant access to cite pages or passages in MLA 8, MLA 7, APA and Chicago citation styles.

    "Portraying himself as an honest, ordinary person helped Lincoln identify with his audiences." (Einhorn, 1992, p. 25).

    "Portraying himself as an honest, ordinary person helped Lincoln identify with his audiences." (Einhorn 25)

    "Portraying himself as an honest, ordinary person helped Lincoln identify with his audiences." (Einhorn 25)

    "Portraying himself as an honest, ordinary person helped Lincoln identify with his audiences."1

    1. Lois J. Einhorn, Abraham Lincoln, the Orator: Penetrating the Lincoln Legend (Westport, CT: Greenwood Press, 1992), 25, http://www.questia.com/read/27419298.

    Cited passage

    Thanks for trying Questia!

    Please continue trying out our research tools, but please note, full functionality is available only to our active members.

    Your work will be lost once you leave this Web page.

    Buy instant access to save your work.

    Already a member? Log in now.

    Search by... Author
    Show... All Results Primary Sources Peer-reviewed

    Oops!

    An unknown error has occurred. Please click the button below to reload the page. If the problem persists, please try again in a little while.