Duke University Medical Center

By Aungst, Heide | Medical Economics, February 2, 2009 | Go to article overview

Duke University Medical Center


Aungst, Heide, Medical Economics


DURHAM, NORTH CAROLINA

In about 10 percent of ovarian cancer cases, the cause is clear: The woman carries a BRCAl or BRCA2 mutation.

But researchers at Duke University Medical Center suspect there's a more common cause of ovarian cancer. That's why they're looking deeper into the genome to find other possible causes.

This line of research- along with providing patients with leading-edge diagnostic tools and treatments, including robotic and laparoscopic surgery- is among the reasons why Duke Medical Center's Division of Gynecologic Oncology is a Clinical Center of Excellence.

In 1999, the Division of Gynecologic Oncology initiated the ongoing North Carolina Ovarian Cancer Study. Since its beginning, more than 1,200 women have enrolled, and their DNA and ovarian cancer risk factor profiles are being compared to controls without the disease. "We're looking for polymorphisms that are more common in women with ovarian cancer than in women who don't have ovarian cancer," says Andrew Berchuck, MD, director of the Division of Gynecologic Oncology.

The ultimate goal, Berchuck says, is to identify women with a genetic predisposition to ovarian cancer. Additional screenings or prophylactic salpingo-oophorectomy might be recommended for this group of women.

"At Duke, we have a very active molecular research program where we're trying to push the envelope, as we work toward better screening, prevention, and treatment," Berchuck says.

The division has translated research from the bench to the bedside in creating a DNA microarray, developed along with colleagues in Duke's Institute for Genome Sciences and Policy, to analyze tumor DNA. …

The rest of this article is only available to active members of Questia

Already a member? Log in now.

Notes for this article

Add a new note
If you are trying to select text to create highlights or citations, remember that you must now click or tap on the first word, and then click or tap on the last word.
One moment ...
Default project is now your active project.
Project items

Items saved from this article

This article has been saved
Highlights (0)
Some of your highlights are legacy items.

Highlights saved before July 30, 2012 will not be displayed on their respective source pages.

You can easily re-create the highlights by opening the book page or article, selecting the text, and clicking “Highlight.”

Citations (0)
Some of your citations are legacy items.

Any citation created before July 30, 2012 will labeled as a “Cited page.” New citations will be saved as cited passages, pages or articles.

We also added the ability to view new citations from your projects or the book or article where you created them.

Notes (0)
Bookmarks (0)

You have no saved items from this article

Project items include:
  • Saved book/article
  • Highlights
  • Quotes/citations
  • Notes
  • Bookmarks
Notes
Cite this article

Cited article

Style
Citations are available only to our active members.
Buy instant access to cite pages or passages in MLA, APA and Chicago citation styles.

(Einhorn, 1992, p. 25)

(Einhorn 25)

1. Lois J. Einhorn, Abraham Lincoln, the Orator: Penetrating the Lincoln Legend (Westport, CT: Greenwood Press, 1992), 25, http://www.questia.com/read/27419298.

Cited article

Duke University Medical Center
Settings

Settings

Typeface
Text size Smaller Larger Reset View mode
Search within

Search within this article

Look up

Look up a word

  • Dictionary
  • Thesaurus
Please submit a word or phrase above.
Print this page

Print this page

Why can't I print more than one page at a time?

Help
Full screen

matching results for page

    Questia reader help

    How to highlight and cite specific passages

    1. Click or tap the first word you want to select.
    2. Click or tap the last word you want to select, and you’ll see everything in between get selected.
    3. You’ll then get a menu of options like creating a highlight or a citation from that passage of text.

    OK, got it!

    Cited passage

    Style
    Citations are available only to our active members.
    Buy instant access to cite pages or passages in MLA, APA and Chicago citation styles.

    "Portraying himself as an honest, ordinary person helped Lincoln identify with his audiences." (Einhorn, 1992, p. 25).

    "Portraying himself as an honest, ordinary person helped Lincoln identify with his audiences." (Einhorn 25)

    "Portraying himself as an honest, ordinary person helped Lincoln identify with his audiences."1

    1. Lois J. Einhorn, Abraham Lincoln, the Orator: Penetrating the Lincoln Legend (Westport, CT: Greenwood Press, 1992), 25, http://www.questia.com/read/27419298.

    Cited passage

    Thanks for trying Questia!

    Please continue trying out our research tools, but please note, full functionality is available only to our active members.

    Your work will be lost once you leave this Web page.

    Buy instant access to save your work.

    Already a member? Log in now.

    Author Advanced search

    Oops!

    An unknown error has occurred. Please click the button below to reload the page. If the problem persists, please try again in a little while.