Morbidity and Mortality Related to Human Immunodeficiency Virus in Canadian Men and Women, 1987-1994

By Weber, Amy E; Hogg, Robert S | Canadian Journal of Public Health, March/April 1999 | Go to article overview

Morbidity and Mortality Related to Human Immunodeficiency Virus in Canadian Men and Women, 1987-1994


Weber, Amy E, Hogg, Robert S, Canadian Journal of Public Health


A B S T R A C T

Objective: To assess the impact of HIV/AIDS on hospitalization and mortality patterns in Canada.

Methods: Hospitalizations and deaths due to HIV/AIDS were compared with select causes of

morbidity and mortality among men and women across provinces, regions and select cities between 1987-94. Patterns of hospitalization and mortality, were characterized by calculating age-specific, standardized rates, rate ratios and potential years of life lost before 65 years.

Results: A total of 28,462 hospitalizations (26,153 in men and 2,309 in women) and 8,739 deaths (8,192 in men and 547 in women) were attributed to HIV/AIDS during the study period. Rates of HIV/AIDS hospitalization were highest for men in Ontario, Quebec and British Columbia, and in Montreal, Toronto and Vancouver; while among women they were highest in Quebec and in Montreal. Toronto and Vancouver. Mortality rates followed a pattern similar to the rates found for hospitalization.

Conclusions: Our analysis reveals the considerable impact of HIV/AIDS on patterns of morbidity and mortality in Canada.

A B R E G E

Ojectif: Mesurer l'impact du VIH/sida sur les tendances des hospitalisations et de la mortalite au Canada.

Methodes: On a compar, les hospitalisations et la mortalite associees au VIH/sida et a d'autres grandes causes de morbidite et de mortalite chez les hommes et les femmes selon les provinces, les regions et certaines villes, entre 1987 et 1994. Les tendances des hospitalisations et de la mortalite ont ete evaluees par le calcul des taux standardises, des taux par tranche d'age et des ratios de taux, et le calcul des annees potentielles de vie perdues avant l'age de 65 ans.

Resultats: En tout, 28 462 hospitalisations (26 153 hommes; 2 309 femmes) et 8 739 deces (8 192 hommes; 547 femmes) ont et, attribues au VIH/sida au cours de la periode de l'etude. Les taux d'hospitalisation associes an VIH/sida chez les hommes ont ete les plus eleves en Ontario, au Quebec et en Colombie Britannique, er dans les villes de Montreal. Toronto et Vancouver; tandis que chez les femmes, les taux d'hospitalisation associes au VIH/sida ont ete plus eleves au Quebec et dans les villes de Montreal, Toronto et Vancouver. Les taux de mortalite ont suivi la meme tendance que les taux d'hospitalisation.

Conclusions: Selon notre analyse, l'impact du H/sida sur la situation de la morbidite et de la mortalite an Canada est considerable.

Over the last decade, HIV infection has emerged as a leading cause of premature morbidity and mortality in many industrialized nations including the United States of America, Canada, much of Western Europe and parts of Oceania. Despite a recent decline in mortality attributed to antiretroviral therapy in the United States, HIV remains the most common underlying cause of death among those aged 25-44 years, accounting for 19% of deaths from all causes in 1996 in this age group.1 Similar rates of high mortality have been reported in men and women in France, Spain, and Italy and in the cities of Amsterdam and London.2-7 In Australia, high rates of mortality have been reported in young adults.8

We have shown the considerable impact of HIV/AIDS on patterns of mortality in Canadians, especially among young adults living in large urban centres.9,10 This work updates our previous research efforts by characterizing the recent as well as the historical impact of HIV/AIDS on mortality and hospitalization. In an effort to better understand these recent trends, we have characterized gender and regional differences in HIV/AIDS morbidity and mortality in Canada over an eight-year period and compared these patterns to those exhibited by other leading causes of death and hospitalization.

METHODS

This analysis was based on data for all hospitalizations and deaths in Canada attributed to HIV/AIDS and other select causes for the years 1987 through 1994. …

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