Learning and Memory: The Behavioral and Biological Substrates

By Isidore Gormezano; Edward A. Wasserman | Go to book overview

of brain weight, neuron loss, hyperactivity, learning deficits, deficiencies in memory function, and perseverative tendencies. These results encourage the further use of this animal model of FAS, particularly to specify better the relationship between alcohol-induced brain damage and behavioral dysfunction. In addition, the model affords the potential to evaluate CNS disruption that is less extreme than cell loss, which may have important implications for lower levels of prenatal alcohol exposure in humans that do not lead to a diagnosis of FAS, but which nevertheless may have adverse effects on the development of the nervous system.


ACKNOWLEDGMENTS

We thank Craig Pleggenkuhle and Bob Halloran for contributing to the behavioral testing, Blake Hamann for assisting with the cell counts, and Sara Hulsether, Jolonda Mahoney, and John Nichols for assisting with the artificial rearing. We also thank Keith Miller for constructing the radial maze.


REFERENCES

Abel E. L. ( 1979). "Prenatal effects of alcohol on adult learning in rats". Pharmacology & Behavior, 10, 239-243.

Abel E. L., & Sokol R. J. ( 1987). "Incidence of fetal alcohol syndrome and economic impact of FAS-related anomalies". Drug & Alcohol Dependence, 19, 51-70.

Altman J. ( 1969). "Autoradiographic and histological studies of postnatal neurogenesis. Ill. Dating the time of production and onset of differentiation of cerebellar microneurons in rats". Journal of Comparative Neurology, 136, 269-294.

Altman J. ( 1972). "Postnatal development of the cerebellar cortex in the rat. II. Phases in the maturation of Purkinje cells and of the molecular layer". Journal of Comparative Neurology, 145, 399-464.

Altman J., & Bayer S. A. ( 1978). "Prenatal development of the cerebellar system in the rat. I. Cytogenesis and histogenesis of the deep nuclei and the cortex of the cerebellum". Journal of Comparative Neurology, 179, 23-48.

Barnes D. E., & Walker D. W. ( 1981). "Prenatal ethanol exposure permanently reduces the number of pyramidal neurons in rat hippocampus". Developmental Brain Research, 1, 333-340.

Bauer-Moffett C., & Altman J. ( 1977). "The effect of ethanol chronically administered to preweanling rats on cerebellar development: A morphological study". Brain Research, 119, 249-268.

Bayer S. A. ( 1980a). "Development of the hippocampal region in the rat. I. Neurogenesis examined with 3H-thymidine autoradiography". Journal of Comparative Neurology, 190, 87-114.

Bayer S. A. ( 1980b). "Development of the hippocampal region in the rat. II. Morphogenesis during embryonic and early postnatal life". Journal of Comparative Neurology, 190, 115-134.

Becker J. T., Walker J. A., & Olton D. S. ( 1980). "Neuroanatomical bases of spatial memory". Brain Research, 200, 307-320.

Bond N. W., & DiGuisto E. L. ( 1978). "Avoidance conditioning and Hebb-Williams maze performance in rats treated prenatally with alcohol". Psychopharmacology, 58, 69-71.

Bonthius D. J., Goodlett C. R.. & West J. R. ( 1988). "Blood alcohol concentration and severity ofmicroencephaly in neonatal rats depend on the pattern of alcohol administration"

-204-

Notes for this page

Add a new note
If you are trying to select text to create highlights or citations, remember that you must now click or tap on the first word, and then click or tap on the last word.
One moment ...
Default project is now your active project.
Project items

Items saved from this book

This book has been saved
Highlights (0)
Some of your highlights are legacy items.

Highlights saved before July 30, 2012 will not be displayed on their respective source pages.

You can easily re-create the highlights by opening the book page or article, selecting the text, and clicking “Highlight.”

Citations (0)
Some of your citations are legacy items.

Any citation created before July 30, 2012 will labeled as a “Cited page.” New citations will be saved as cited passages, pages or articles.

We also added the ability to view new citations from your projects or the book or article where you created them.

Notes (0)
Bookmarks (0)

You have no saved items from this book

Project items include:
  • Saved book/article
  • Highlights
  • Quotes/citations
  • Notes
  • Bookmarks
Notes
Cite this page

Cited page

Style
Citations are available only to our active members.
Buy instant access to cite pages or passages in MLA, APA and Chicago citation styles.

(Einhorn, 1992, p. 25)

(Einhorn 25)

1. Lois J. Einhorn, Abraham Lincoln, the Orator: Penetrating the Lincoln Legend (Westport, CT: Greenwood Press, 1992), 25, http://www.questia.com/read/27419298.

Cited page

Bookmark this page
Learning and Memory: The Behavioral and Biological Substrates
Table of contents

Table of contents

Settings

Settings

Typeface
Text size Smaller Larger Reset View mode
Search within

Search within this book

Look up

Look up a word

  • Dictionary
  • Thesaurus
Please submit a word or phrase above.
Print this page

Print this page

Why can't I print more than one page at a time?

Help
Full screen
/ 416

matching results for page

    Questia reader help

    How to highlight and cite specific passages

    1. Click or tap the first word you want to select.
    2. Click or tap the last word you want to select, and you’ll see everything in between get selected.
    3. You’ll then get a menu of options like creating a highlight or a citation from that passage of text.

    OK, got it!

    Cited passage

    Style
    Citations are available only to our active members.
    Buy instant access to cite pages or passages in MLA, APA and Chicago citation styles.

    "Portraying himself as an honest, ordinary person helped Lincoln identify with his audiences." (Einhorn, 1992, p. 25).

    "Portraying himself as an honest, ordinary person helped Lincoln identify with his audiences." (Einhorn 25)

    "Portraying himself as an honest, ordinary person helped Lincoln identify with his audiences."1

    1. Lois J. Einhorn, Abraham Lincoln, the Orator: Penetrating the Lincoln Legend (Westport, CT: Greenwood Press, 1992), 25, http://www.questia.com/read/27419298.

    Cited passage

    Thanks for trying Questia!

    Please continue trying out our research tools, but please note, full functionality is available only to our active members.

    Your work will be lost once you leave this Web page.

    Buy instant access to save your work.

    Already a member? Log in now.

    Oops!

    An unknown error has occurred. Please click the button below to reload the page. If the problem persists, please try again in a little while.